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Heterogeneous matrix stiffness regulates the cancer stem-like cell phenotype in hepatocellular carcinoma

BACKGROUND: Solid tumors are stiffer than their surrounding normal tissues; however, their interior stiffness is not uniform. Under certain conditions, cancer cells can acquire stem-like phenotypes. However, it remains unclear how the heterogeneous physical microenvironment affects stemness expressi...

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Detalles Bibliográficos
Autores principales:	Wei, Jiayun, Yao, Jia, Yang, Chendong, Mao, Yongcui, Zhu, Dan, Xie, Ye, Liu, Pinyan, Yan, Mengchao, Ren, Longfei, Lin, Yan, Zheng, Qiuxia, Li, Xun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9719217/ https://www.ncbi.nlm.nih.gov/pubmed/36463272 http://dx.doi.org/10.1186/s12967-022-03778-w

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