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Epigenetic silencing of JAM3 promotes esophageal cancer development by activating Wnt signaling

BACKGROUND: The role of JAM3 in different tumors is controversial. The epigenetic regulation and the mechanism of JAM3 remain to be elucidated in human esophageal cancer (EC). METHODS: Eleven EC cell lines, 49 cases of esophageal intraepithelial neoplasia (EIN) and 760 cases of primary EC samples we...

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Detalles Bibliográficos
Autores principales: Yang, Weili, Guo, Chao, Herman, James G., Zhu, Cheng, Lv, Honghui, Su, Xiaomo, Zhang, Lirong, Zhang, Meiying, Guo, Mingzhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9719220/
https://www.ncbi.nlm.nih.gov/pubmed/36461092
http://dx.doi.org/10.1186/s13148-022-01388-3