Eribulin normalizes pancreatic cancer-associated fibroblasts by simulating selected features of TGFβ inhibition

BACKGROUND: Less than 11% of pancreatic cancer patients survive 5-years post-diagnosis. The unique biology of pancreatic cancer includes a significant expansion of its desmoplastic tumor microenvironment, wherein cancer-associated fibroblasts (CAFs) and their self-produced extracellular matrix are k...

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Detalles Bibliográficos
Autores principales: Luong, Tiffany, Cukierman, Edna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9719234/
https://www.ncbi.nlm.nih.gov/pubmed/36461015
http://dx.doi.org/10.1186/s12885-022-10330-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9719234/
https://www.ncbi.nlm.nih.gov/pubmed/36461015
http://dx.doi.org/10.1186/s12885-022-10330-y

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