Cargando…
Eribulin normalizes pancreatic cancer-associated fibroblasts by simulating selected features of TGFβ inhibition
BACKGROUND: Less than 11% of pancreatic cancer patients survive 5-years post-diagnosis. The unique biology of pancreatic cancer includes a significant expansion of its desmoplastic tumor microenvironment, wherein cancer-associated fibroblasts (CAFs) and their self-produced extracellular matrix are k...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9719234/ https://www.ncbi.nlm.nih.gov/pubmed/36461015 http://dx.doi.org/10.1186/s12885-022-10330-y |