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Intranasal Vaccination with rePcrV Protects against Pseudomonas aeruginosa and Generates Lung Tissue-Resident Memory T Cells

Tissue-resident memory T (T(RM)) cells are immune sentinels that bear a key role in the local immune system and rapidly respond to infection. Our previous studies showed that mucosal immunization via intranasal pathways was more effective than intramuscular route. However, the mechanism of enhanced...

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Detalles Bibliográficos
Autores principales: Ou, Yangxue, Wang, Ying, Yu, Ting, Cui, Zhiyuan, Chen, Xin, Zhang, Weijun, Zou, Quanming, Gu, Jiang, Zuo, Qianfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9719435/
https://www.ncbi.nlm.nih.gov/pubmed/36471700
http://dx.doi.org/10.1155/2022/1403788