Transcriptomics indicate nuclear division and cell adhesion not recapitulated in MCF7 and MCF10A compared to luminal A breast tumours

Breast cancer (BC) cell lines are useful experimental models to understand cancer biology. Yet, their relevance to modelling cancer remains unclear. To better understand the tumour-modelling efficacy of cell lines, we performed RNA-seq analyses on a combined dataset of 2D and 3D cultures of tumourig...

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Detalles Bibliográficos
Autores principales: Goh, Jeremy Joon Ho, Goh, Corinna Jie Hui, Lim, Qian Wei, Zhang, Songjing, Koh, Cheng-Gee, Chiam, Keng-Hwee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9719475/
https://www.ncbi.nlm.nih.gov/pubmed/36463288
http://dx.doi.org/10.1038/s41598-022-24511-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9719475/
https://www.ncbi.nlm.nih.gov/pubmed/36463288
http://dx.doi.org/10.1038/s41598-022-24511-z

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