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Transcriptomics indicate nuclear division and cell adhesion not recapitulated in MCF7 and MCF10A compared to luminal A breast tumours

Breast cancer (BC) cell lines are useful experimental models to understand cancer biology. Yet, their relevance to modelling cancer remains unclear. To better understand the tumour-modelling efficacy of cell lines, we performed RNA-seq analyses on a combined dataset of 2D and 3D cultures of tumourig...

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Detalles Bibliográficos
Autores principales:	Goh, Jeremy Joon Ho, Goh, Corinna Jie Hui, Lim, Qian Wei, Zhang, Songjing, Koh, Cheng-Gee, Chiam, Keng-Hwee
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9719475/ https://www.ncbi.nlm.nih.gov/pubmed/36463288 http://dx.doi.org/10.1038/s41598-022-24511-z

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