SSTR2 as an anatomical imaging marker and a safety switch to monitor and manage CAR T cell toxicity

The ability to image adoptively transferred T cells in the body and to eliminate them to avoid toxicity will be vital for chimeric antigen receptor (CAR) T cell therapy, particularly against solid tumors with higher risk of off-tumor toxicity. Previously, we have demonstrated the utility of somatost...

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Detalles Bibliográficos
Autores principales: Alcaina, Yago, Yang, Yanping, Vedvyas, Yogindra, McCloskey, Jaclyn E., Jin, Moonsoo M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9719480/
https://www.ncbi.nlm.nih.gov/pubmed/36463361
http://dx.doi.org/10.1038/s41598-022-25224-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9719480/
https://www.ncbi.nlm.nih.gov/pubmed/36463361
http://dx.doi.org/10.1038/s41598-022-25224-z

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