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SSTR2 as an anatomical imaging marker and a safety switch to monitor and manage CAR T cell toxicity
The ability to image adoptively transferred T cells in the body and to eliminate them to avoid toxicity will be vital for chimeric antigen receptor (CAR) T cell therapy, particularly against solid tumors with higher risk of off-tumor toxicity. Previously, we have demonstrated the utility of somatost...
Autores principales: | Alcaina, Yago, Yang, Yanping, Vedvyas, Yogindra, McCloskey, Jaclyn E., Jin, Moonsoo M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9719480/ https://www.ncbi.nlm.nih.gov/pubmed/36463361 http://dx.doi.org/10.1038/s41598-022-25224-z |
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