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Setd2 supports GATA3(+)ST2(+) thymic-derived Treg cells and suppresses intestinal inflammation
Treg cells acquire distinct transcriptional properties to suppress specific inflammatory responses. Transcription characteristics of Treg cells are regulated by epigenetic modifications, the mechanism of which remains obscure. Here, we report that Setd2, a histone H3K36 methyltransferase, is importa...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9719510/ https://www.ncbi.nlm.nih.gov/pubmed/36463230 http://dx.doi.org/10.1038/s41467-022-35250-0 |