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Setd2 supports GATA3(+)ST2(+) thymic-derived Treg cells and suppresses intestinal inflammation

Treg cells acquire distinct transcriptional properties to suppress specific inflammatory responses. Transcription characteristics of Treg cells are regulated by epigenetic modifications, the mechanism of which remains obscure. Here, we report that Setd2, a histone H3K36 methyltransferase, is importa...

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Detalles Bibliográficos
Autores principales: Ding, Zhaoyun, Cai, Ting, Tang, Jupei, Sun, Hanxiao, Qi, Xinyi, Zhang, Yunpeng, Ji, Yan, Yuan, Liyun, Chang, Huidan, Ma, Yanhui, Zhou, Hong, Li, Li, Sheng, Huiming, Qiu, Ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9719510/
https://www.ncbi.nlm.nih.gov/pubmed/36463230
http://dx.doi.org/10.1038/s41467-022-35250-0

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