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Non-classical ferroptosis inhibition by a small molecule targeting PHB2

Ferroptosis is a new type of programmed cell death characterized by iron-dependent lipid peroxidation. Ferroptosis inhibition is thought as a promising therapeutic strategy for a variety of diseases. Currently, a majority of known ferroptosis inhibitors belong to either antioxidants or iron-chelator...

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Detalles Bibliográficos
Autores principales: Yang, Wei, Mu, Bo, You, Jing, Tian, Chenyu, Bin, Huachao, Xu, Zhiqiang, Zhang, Liting, Ma, Ronggang, Wu, Ming, Zhang, Guo, Huang, Chong, Li, Linli, Shao, Zhenhua, Dai, Lunzhi, Désaubry, Laurent, Yang, Shengyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9719519/
https://www.ncbi.nlm.nih.gov/pubmed/36463308
http://dx.doi.org/10.1038/s41467-022-35294-2