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Excess iodine exposure acutely increases salivary iodide and antimicrobial hypoiodous acid concentrations in humans

The lactoperoxidase (LPO)-hydrogen peroxide-halides reaction (LPO system) converts iodide and thiocyanate (SCN(−)) into hypoiodous acid (HOI) and hypothiocyanite (OSCN(−)), respectively. Since this system has been implicated in defense of the airways and oropharynx from microbial invasion, in this p...

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Detalles Bibliográficos
Autores principales: Akiba, Yasutada, Leung, Angela M., Bashir, Muhammad-Tariq, Ebrahimi, Ramin, Currier, Jesse W., Neverova, Natalia, Kaunitz, Jonathan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9719529/
https://www.ncbi.nlm.nih.gov/pubmed/36463312
http://dx.doi.org/10.1038/s41598-022-23803-8