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The mechanism of BUD13 m6A methylation mediated MBNL1-phosphorylation by CDK12 regulating the vasculogenic mimicry in glioblastoma cells

Vasculogenic mimicry (VM) is an endothelium-independent tumor microcirculation that provides adequate blood supply for tumor growth. The presence of VM greatly hinders the treatment of glioblastoma (GBM) with anti-angiogenic drugs. Therefore, targeting VM formation may be a feasible therapeutic stra...

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Detalles Bibliográficos
Autores principales: Liu, Meichen, Ruan, Xuelei, Liu, Xiaobai, Dong, Weiwei, Wang, Di, Yang, Chunqing, Liu, Libo, Wang, Ping, Zhang, Mengyang, Xue, Yixue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9719550/
https://www.ncbi.nlm.nih.gov/pubmed/36463205
http://dx.doi.org/10.1038/s41419-022-05426-z