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Anti-osteopontin therapy leads to improved edema and infarct size in a murine model of ischemic stroke

Ischemic stroke is a serious neurological disorder that is associated with dysregulation of the neurovascular unit (NVU) and impairment of the blood–brain barrier (BBB). Paradoxically, reperfusion therapies can aggravate NVU and BBB dysfunction, leading to deleterious consequences in addition to the...

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Detalles Bibliográficos
Autores principales: Spitzer, Daniel, Puetz, Tim, Armbrust, Moritz, Dunst, Maika, Macas, Jadranka, Croll, Florian, Plate, Karl-Heinz, Reiss, Yvonne, Liebner, Stefan, Harter, Patrick N., Guérit, Sylvaine, Devraj, Kavi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9719559/
https://www.ncbi.nlm.nih.gov/pubmed/36463381
http://dx.doi.org/10.1038/s41598-022-25245-8