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Anti-osteopontin therapy leads to improved edema and infarct size in a murine model of ischemic stroke
Ischemic stroke is a serious neurological disorder that is associated with dysregulation of the neurovascular unit (NVU) and impairment of the blood–brain barrier (BBB). Paradoxically, reperfusion therapies can aggravate NVU and BBB dysfunction, leading to deleterious consequences in addition to the...
Autores principales: | Spitzer, Daniel, Puetz, Tim, Armbrust, Moritz, Dunst, Maika, Macas, Jadranka, Croll, Florian, Plate, Karl-Heinz, Reiss, Yvonne, Liebner, Stefan, Harter, Patrick N., Guérit, Sylvaine, Devraj, Kavi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9719559/ https://www.ncbi.nlm.nih.gov/pubmed/36463381 http://dx.doi.org/10.1038/s41598-022-25245-8 |
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