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TREM2 activation alleviates neural damage via Akt/CREB/BDNF signalling after traumatic brain injury in mice

BACKGROUND: Neuroinflammation is one of the most important processes in secondary injury after traumatic brain injury (TBI). Triggering receptor expressed on myeloid cells 2 (TREM2) has been proven to exert neuroprotective effects in neurodegenerative diseases and stroke by modulating neuroinflammat...

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Detalles Bibliográficos
Autores principales: Yan, Jin, Zhang, Yuan, Wang, Lin, Li, Zhao, Tang, Shuang, Wang, Yingwen, Gu, Nina, Sun, Xiaochuan, Li, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9719652/
https://www.ncbi.nlm.nih.gov/pubmed/36463233
http://dx.doi.org/10.1186/s12974-022-02651-3