Nanoparticles-mediated CRISPR-Cas9 gene therapy in inherited retinal diseases: applications, challenges, and emerging opportunities

Inherited Retinal Diseases (IRDs) are considered one of the leading causes of blindness worldwide. However, the majority of them still lack a safe and effective treatment due to their complexity and genetic heterogeneity. Recently, gene therapy is gaining importance as an efficient strategy to addre...

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Detalles Bibliográficos
Autores principales: Chien, Yueh, Hsiao, Yu-Jer, Chou, Shih-Jie, Lin, Ting-Yi, Yarmishyn, Aliaksandr A., Lai, Wei-Yi, Lee, Meng-Shiue, Lin, Yi-Ying, Lin, Tzu-Wei, Hwang, De-Kuang, Lin, Tai-Chi, Chiou, Shih-Hwa, Chen, Shih-Jen, Yang, Yi-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9719668/
https://www.ncbi.nlm.nih.gov/pubmed/36463195
http://dx.doi.org/10.1186/s12951-022-01717-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9719668/
https://www.ncbi.nlm.nih.gov/pubmed/36463195
http://dx.doi.org/10.1186/s12951-022-01717-x

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