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Enhancement of antitumor immune response by radiation therapy combined with dual immune checkpoint inhibitor in a metastatic model of HER2-positive murine tumor

PURPOSE: Treatments for metastatic human epidermal growth factor receptor 2 (HER2)-positive tumors are improving but remain inadequate. We investigated activating antitumor immune response by combining radiation therapy with immune checkpoint inhibitors using mouse tumors overexpressing HER2, a pivo...

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Detalles Bibliográficos
Autores principales: Misaki, Sayaka, Murata, Satoshi, Shimoji, Miyuki, Iwai, Takayasu, Sihombing, Andreas Michael, Aoki, Ken, Takahashi, Yutaka, Watanabe, Yoshiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9719888/
https://www.ncbi.nlm.nih.gov/pubmed/35763240
http://dx.doi.org/10.1007/s11604-022-01303-z