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Enhancement of recombinant human IL-24 (rhIL-24) protein production from site-specific integrated engineered CHO cells by sodium butyrate treatment

Interleukin-24 (IL-24) has specific inhibitory effects on the proliferation of various tumor cells with almost no toxicity to normal cells. The antitumor activity of recombinant human IL-24 protein produced in mammalian cells is much higher than that of bacteria, but its expression level is extremel...

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Detalles Bibliográficos
Autores principales: Hua, Jilei, Xu, Hanli, Zhang, Yao, Ge, Jianlin, Liu, Mengzhe, Wang, Yuqi, Wei, Yuexian, Shi, Yinan, Hou, LingLing, Jiang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9719890/
https://www.ncbi.nlm.nih.gov/pubmed/36282328
http://dx.doi.org/10.1007/s00449-022-02801-0