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The catalytic mechanism, metal dependence, substrate specificity, and biodiversity of ribonuclease H
Ribonucleoside monophosphates are inevitably misincorporated into the DNA genome inside cells, and they need to be excised to avoid chromosome instability. Ribonucleases H (RNases H) are enzymes that specifically hydrolyze the RNA strand of RNA/DNA hybrids or the RNA moiety from DNA containing a str...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9719913/ https://www.ncbi.nlm.nih.gov/pubmed/36478866 http://dx.doi.org/10.3389/fmicb.2022.1034811 |