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The SARS-CoV-2 spike S375F mutation characterizes the Omicron BA.1 variant
Recent studies have revealed the unique virological characteristics of Omicron, particularly those of its spike protein, such as less cleavage efficacy in cells, reduced ACE2 binding affinity, and poor fusogenicity. However, it remains unclear which mutation(s) determine these three virological char...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9719929/ https://www.ncbi.nlm.nih.gov/pubmed/36507224 http://dx.doi.org/10.1016/j.isci.2022.105720 |