The SARS-CoV-2 spike S375F mutation characterizes the Omicron BA.1 variant

Recent studies have revealed the unique virological characteristics of Omicron, particularly those of its spike protein, such as less cleavage efficacy in cells, reduced ACE2 binding affinity, and poor fusogenicity. However, it remains unclear which mutation(s) determine these three virological char...

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Detalles Bibliográficos
Autores principales: Kimura, Izumi, Yamasoba, Daichi, Nasser, Hesham, Zahradnik, Jiri, Kosugi, Yusuke, Wu, Jiaqi, Nagata, Kayoko, Uriu, Keiya, Tanaka, Yuri L., Ito, Jumpei, Shimizu, Ryo, Tan, Toong Seng, Butlertanaka, Erika P., Asakura, Hiroyuki, Sadamasu, Kenji, Yoshimura, Kazuhisa, Ueno, Takamasa, Takaori-Kondo, Akifumi, Schreiber, Gideon, Toyoda, Mako, Shirakawa, Kotaro, Irie, Takashi, Saito, Akatsuki, Nakagawa, So, Ikeda, Terumasa, Sato, Kei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9719929/
https://www.ncbi.nlm.nih.gov/pubmed/36507224
http://dx.doi.org/10.1016/j.isci.2022.105720

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