Galectin-9/Tim-3 pathway mediates dopaminergic neurodegeneration in MPTP-induced mouse model of Parkinson’s disease

Galectin-9 (Gal-9) is a crucial immunoregulatory mediator in the central nervous system. Microglial activation and neuroinflammation play a key role in the degeneration of dopaminergic neurons in the substantia nigra (SN) in Parkinson’s disease (PD). However, it remains unknown whether Gal-9 is invo...

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Detalles Bibliográficos
Autores principales: Peng, Qinyu, Zhang, Guoxin, Guo, Xiaodi, Dai, Lijun, Xiong, Min, Zhang, Zhaohui, Chen, Liam, Zhang, Zhentao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9719949/
https://www.ncbi.nlm.nih.gov/pubmed/36479526
http://dx.doi.org/10.3389/fnmol.2022.1046992

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9719949/
https://www.ncbi.nlm.nih.gov/pubmed/36479526
http://dx.doi.org/10.3389/fnmol.2022.1046992

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