Paeoniflorin alleviates 17α-ethinylestradiol-induced cholestasis via the farnesoid X receptor-mediated bile acid homeostasis signaling pathway in rats

Cholestasis, characterized by disturbance of bile formation, is a common pathological condition that can induce several serious liver diseases. As a kind of trigger, estrogen-induced cholestasis belongs to drug-induced cholestasis. Paeoniflorin is the most abundant bioactive constituent in Paeonia l...

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Detalles Bibliográficos
Autores principales: Wang, Rulin, Yuan, Tengteng, Sun, Jing, Yang, Menghuan, Chen, Yunna, Wang, Lei, Wang, Yanyan, Chen, Weidong, Peng, Daiyin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9719974/
https://www.ncbi.nlm.nih.gov/pubmed/36479204
http://dx.doi.org/10.3389/fphar.2022.1064653

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9719974/
https://www.ncbi.nlm.nih.gov/pubmed/36479204
http://dx.doi.org/10.3389/fphar.2022.1064653

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