Cargando…

Paeoniflorin alleviates 17α-ethinylestradiol-induced cholestasis via the farnesoid X receptor-mediated bile acid homeostasis signaling pathway in rats

Cholestasis, characterized by disturbance of bile formation, is a common pathological condition that can induce several serious liver diseases. As a kind of trigger, estrogen-induced cholestasis belongs to drug-induced cholestasis. Paeoniflorin is the most abundant bioactive constituent in Paeonia l...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Rulin, Yuan, Tengteng, Sun, Jing, Yang, Menghuan, Chen, Yunna, Wang, Lei, Wang, Yanyan, Chen, Weidong, Peng, Daiyin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9719974/ https://www.ncbi.nlm.nih.gov/pubmed/36479204 http://dx.doi.org/10.3389/fphar.2022.1064653

Ejemplares similares

Baicalin Protects Against 17α-Ethinylestradiol-Induced Cholestasis via the Sirtuin 1/Hepatic Nuclear Receptor-1α/Farnesoid X Receptor Pathway
por: Yang, Jinyu, et al.
Publicado: (2020)

Labetalol and soluble endoglin aggravate bile acid retention in mice with ethinylestradiol-induced cholestasis
por: Cristina Igreja Sá, Ivone, et al.
Publicado: (2023)

Calculus Bovis Sativus Improves Bile Acid Homeostasis via Farnesoid X Receptor-Mediated Signaling in Rats With Estrogen-Induced Cholestasis
por: Xiang, Dong, et al.
Publicado: (2019)

Kinsenoside Alleviates 17α-Ethinylestradiol-Induced Cholestatic Liver Injury in Rats by Inhibiting Inflammatory Responses and Regulating FXR-Mediated Bile Acid Homeostasis
por: Ming, Jiaxiong, et al.
Publicado: (2021)

Protective effect of heme oxygenase induction in ethinylestradiol-induced cholestasis
por: Muchova, Lucie, et al.
Publicado: (2015)

Effect of YHHJ on the expression of the hepatocellular bile acid transporters multidrug resistance-associated protein 2 and bile salt export pump in ethinylestradiol-induced cholestasis
por: Liu, Jia, et al.
Publicado: (2018)

Arbutin Alleviates the Liver Injury of α-Naphthylisothiocyanate-induced Cholestasis Through Farnesoid X Receptor Activation
por: Wu, Peijie, et al.
Publicado: (2021)

Mechanism and Active Components of Qingre Lidan Tablets Alleviate Intrahepatic Cholestasis by Activating the Farnesoid X Receptor
por: Xia, Yafei, et al.
Publicado: (2022)

Huangqi Decoction Alleviates Alpha-Naphthylisothiocyanate Induced Intrahepatic Cholestasis by Reversing Disordered Bile Acid and Glutathione Homeostasis in Mice
por: Wu, Jia-Sheng, et al.
Publicado: (2017)

A novel role for farnesoid X receptor in the bile acid‐mediated intestinal glucose homeostasis
por: Zhao, Long, et al.
Publicado: (2020)

Regulation of Chromatin Accessibility by the Farnesoid X Receptor Is Essential for Circadian and Bile Acid Homeostasis In Vivo
por: Hassan, Haider M., et al.
Publicado: (2022)

Farnesoid X Receptor as Target for Therapies to Treat Cholestasis-Induced Liver Injury
por: Petrescu, Anca D., et al.
Publicado: (2021)

β-Defensin 1 Is Prominent in the Liver and Induced During Cholestasis by Bilirubin and Bile Acids via Farnesoid X Receptor and Constitutive Androstane Receptor
por: Klag, Thomas, et al.
Publicado: (2018)

Farnesoid X receptor and bile acids regulate vitamin A storage
por: Saeed, Ali, et al.
Publicado: (2019)

Cholestasis: exploring the triangular relationship of gut microbiota-bile acid-cholestasis and the potential probiotic strategies
por: Yu, Leilei, et al.
Publicado: (2023)

Farnesoid X Receptor, Bile Acid Metabolism, and Gut Microbiota
por: Mori, Hideki, et al.
Publicado: (2022)

Paeoniflorin Alleviates Abnormalities in Rats with Functional Dyspepsia by Stimulating the Release of Acetylcholine
por: Zou, Xuan, et al.
Publicado: (2020)

Manganese‐oxidizing bacteria mediate the degradation of 17α‐ethinylestradiol
por: Sabirova, Julia S., et al.
Publicado: (2008)

Detecting Traces of 17α-Ethinylestradiol in Complex Water Matrices
por: Zagalo, Paulo M, et al.
Publicado: (2020)

Transcriptomic and Physiological Responses of Chlorella pyrenoidosa during Exposure to 17α-Ethinylestradiol
por: Zhang, Yurui, et al.
Publicado: (2022)

Irisin Is Controlled by Farnesoid X Receptor and Regulates Cholesterol Homeostasis
por: Li, Hong, et al.
Publicado: (2019)

Constitutive Androstane Receptor Differentially Regulates Bile Acid Homeostasis in Mouse Models of Intrahepatic Cholestasis
por: Kim, Kang Ho, et al.
Publicado: (2018)

Population pharmacokinetic model to generate mechanistic insights in bile acid homeostasis and drug-induced cholestasis
por: de Bruijn, Véronique M. P., et al.
Publicado: (2022)

Bile Acids in Intrahepatic Cholestasis of Pregnancy
por: Majsterek, Maciej, et al.
Publicado: (2022)

Farnesoid X receptor agonist tropifexor attenuates cholestasis in a randomised trial in patients with primary biliary cholangitis
por: Schramm, Christoph, et al.
Publicado: (2022)

Obeticholic acid, a selective farnesoid X receptor agonist, regulates bile acid homeostasis in sandwich‐cultured human hepatocytes
por: Zhang, Yuanyuan, et al.
Publicado: (2017)

Role of farnesoid X receptor and bile acids in alcoholic liver disease
por: Manley, Sharon, et al.
Publicado: (2015)

Role of Farnesoid X Receptor and Bile Acids in Hepatic Tumor Development
por: Takahashi, Shogo, et al.
Publicado: (2018)

Primary Biliary Cholangitis and Bile Acid Farnesoid X Receptor Agonists
por: Abenavoli, Ludovico, et al.
Publicado: (2020)

Adsorption Behaviors of 17α-Ethinylestradiol in Sediment-Water System in Northern Taihu Lake, China
por: Wang, Yonghua, et al.
Publicado: (2014)

Polygoni Multiflori Radix interferes with bile acid metabolism homeostasis by inhibiting Fxr transcription, leading to cholestasis
por: Dai, Yihang, et al.
Publicado: (2023)

Promoter DNA Methylation of Farnesoid X Receptor and Pregnane X Receptor Modulates the Intrahepatic Cholestasis of Pregnancy Phenotype
por: Cabrerizo, Romina, et al.
Publicado: (2014)

Effects and mechanism of the bile acid (farnesoid X) receptor on the Wnt/β-catenin signaling pathway in colon cancer
por: Mao, Jiayu, et al.
Publicado: (2020)

Farnesoid X receptor, the bile acid sensing nuclear receptor, in liver regeneration
por: Li, Guodong, et al.
Publicado: (2015)

Bile Diversion Improves Metabolic Phenotype Dependent on Farnesoid X Receptor (FXR)
por: Pierre, Joseph F., et al.
Publicado: (2019)

Farnesoid X receptor activation by bile acids suppresses lipid peroxidation and ferroptosis
por: Tschuck, Juliane, et al.
Publicado: (2023)

Removal of ecotoxicity of 17α-ethinylestradiol using TAML/peroxide water treatment
por: Mills, Matthew R., et al.
Publicado: (2015)

Intrahepatic Cholestasis of Pregnancy Levels of Sulfated Progesterone Metabolites Inhibit Farnesoid X Receptor Resulting in a Cholestatic Phenotype
por: Abu-Hayyeh, Shadi, et al.
Publicado: (2013)

Elevated Bile Acid Is Associated with Worsened Impaired Glucose Homeostasis in Pancreatic Ductal Adenocarcinoma Patients with Extrahepatic Cholestasis through Increased Hepatic Insulin Clearance
por: Yang, Jie, et al.
Publicado: (2023)

Biochemical profile of bile fluid in patients with malignant cholestasis in comparison with cholestasis due to gall stone
por: Taheri, Hassan, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_bh9h04hj8ilt8aju9fn45g7tfv