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Enzymatically dissociated muscle fibers display rapid dedifferentiation and impaired mitochondrial calcium control
Cells rapidly lose their physiological phenotype upon disruption of their extracellular matrix (ECM)-intracellular cytoskeleton interactions. By comparing adult mouse skeletal muscle fibers, isolated either by mechanical dissection or by collagenase-induced ECM digestion, we investigated acute effec...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9720020/ https://www.ncbi.nlm.nih.gov/pubmed/36479146 http://dx.doi.org/10.1016/j.isci.2022.105654 |