Cargando…

Enzymatically dissociated muscle fibers display rapid dedifferentiation and impaired mitochondrial calcium control

Cells rapidly lose their physiological phenotype upon disruption of their extracellular matrix (ECM)-intracellular cytoskeleton interactions. By comparing adult mouse skeletal muscle fibers, isolated either by mechanical dissection or by collagenase-induced ECM digestion, we investigated acute effec...

Descripción completa

Detalles Bibliográficos
Autores principales: Gineste, Charlotte, Youhanna, Sonia, Vorrink, Sabine U., Henriksson, Sara, Hernández, Andrés, Cheng, Arthur J., Chaillou, Thomas, Buttgereit, Andreas, Schneidereit, Dominik, Friedrich, Oliver, Hultenby, Kjell, Bruton, Joseph D., Ivarsson, Niklas, Sandblad, Linda, Lauschke, Volker M., Westerblad, Håkan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9720020/
https://www.ncbi.nlm.nih.gov/pubmed/36479146
http://dx.doi.org/10.1016/j.isci.2022.105654