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Enzymatically dissociated muscle fibers display rapid dedifferentiation and impaired mitochondrial calcium control
Cells rapidly lose their physiological phenotype upon disruption of their extracellular matrix (ECM)-intracellular cytoskeleton interactions. By comparing adult mouse skeletal muscle fibers, isolated either by mechanical dissection or by collagenase-induced ECM digestion, we investigated acute effec...
Autores principales: | Gineste, Charlotte, Youhanna, Sonia, Vorrink, Sabine U., Henriksson, Sara, Hernández, Andrés, Cheng, Arthur J., Chaillou, Thomas, Buttgereit, Andreas, Schneidereit, Dominik, Friedrich, Oliver, Hultenby, Kjell, Bruton, Joseph D., Ivarsson, Niklas, Sandblad, Linda, Lauschke, Volker M., Westerblad, Håkan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9720020/ https://www.ncbi.nlm.nih.gov/pubmed/36479146 http://dx.doi.org/10.1016/j.isci.2022.105654 |
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