Cargando…

Directed Evolution of Soluble α-1,2-Fucosyltransferase Using Kanamycin Resistance Protein as a Phenotypic Reporter for Efficient Production of 2'-Fucosyllactose

2'-Fucosyllactose (2'-FL), the most abundant fucosylated oligosaccharide in human milk, has multiple beneficial effects on human health. However, its biosynthesis by metabolically engineered Escherichia coli is often hampered owing to the insolubility and instability of α-1,2-fucosyltransf...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shin, Jonghyeok, Kim, Seungjoo, Park, Wonbeom, Jin, Kyoung Chan, Kim, Sun-Ki, Kweon, Dae-Hyuk
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Korean Society for Microbiology and Biotechnology 2022
Materias:	Research article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9720067/ https://www.ncbi.nlm.nih.gov/pubmed/36437520 http://dx.doi.org/10.4014/jmb.2209.09018

Ejemplares similares

Development of fluorescent Escherichia coli for a whole-cell sensor of 2ʹ-fucosyllactose
por: Shin, Jonghyeok, et al.
Publicado: (2020)

Improved production of 2′-fucosyllactose in engineered Saccharomyces cerevisiae expressing a putative α-1, 2-fucosyltransferase from Bacillus cereus
por: Xu, Mingyuan, et al.
Publicado: (2021)

Multi‐level metabolic engineering of Escherichia coli for high‐titer biosynthesis of 2′‐fucosyllactose and 3‐fucosyllactose
por: Li, Mengli, et al.
Publicado: (2022)

Production of a human milk oligosaccharide 2′-fucosyllactose by metabolically engineered Saccharomyces cerevisiae
por: Yu, Sora, et al.
Publicado: (2018)

Modulation of kanamycin B and kanamycin A biosynthesis in Streptomyces kanamyceticus via metabolic engineering
por: Gao, Wenli, et al.
Publicado: (2017)

Design, Synthesis, and Bioassay of 2′-Modified Kanamycin A
por: Yan, Ribai, et al.
Publicado: (2022)

Telmisartan Attenuates Kanamycin-Induced Ototoxicity in Rats
por: Lee, Chang Ho, et al.
Publicado: (2021)

Immunomodulatory and Prebiotic Effects of 2′-Fucosyllactose in Suckling Rats
por: Azagra-Boronat, Ignasi, et al.
Publicado: (2019)

2′-Fucosyllactose and 3-Fucosyllactose Alleviates Interleukin-6-Induced Barrier Dysfunction and Dextran Sodium Sulfate-Induced Colitis by Improving Intestinal Barrier Function and Modulating the Intestinal Microbiome
por: Kim, Yeon-Ji, et al.
Publicado: (2023)

Strain-specific strategies of 2′-fucosyllactose, 3-fucosyllactose, and difucosyllactose assimilation by Bifidobacterium longum subsp. infantis Bi-26 and ATCC 15697
por: Zabel, Bryan E., et al.
Publicado: (2020)

Determination of 2′-Fucosyllactose and Lacto-N-neotetraose in Infant Formula
por: Austin, Sean, et al.
Publicado: (2018)

Alleviation of Intestinal Inflammation by Oral Supplementation With 2-Fucosyllactose in Mice
por: Grabinger, Thomas, et al.
Publicado: (2019)

Engineered Bacillus subtilis for the de novo production of 2′-fucosyllactose
por: Zhang, Quanwei, et al.
Publicado: (2022)

Efficient production of 2′-fucosyllactose in unconventional yeast Yarrowia lipolytica
por: Zhang, Yan, et al.
Publicado: (2023)

Neuron-recognizable characteristics of peptides recombined using a neuronal binding domain of botulinum neurotoxin
por: Kim, Hye Rin, et al.
Publicado: (2022)

Quantifying the human milk oligosaccharides 2’‐fucosyllactose and 3‐fucosyllactose in different food applications by high‐performance liquid chromatography with refractive index detection
por: Christensen, Anne Støvlbæk, et al.
Publicado: (2020)

Widespread Gene Conversion of Alpha-2-Fucosyltransferase Genes in Mammals
por: Abrantes, Joana, et al.
Publicado: (2009)

Clinical significance and biological function of fucosyltransferase 2 in lung adenocarcinoma
por: Zhou, Wenyuan, et al.
Publicado: (2017)

Protein O-Fucosyltransferase 2 Is Not Essential for Plasmodium berghei Development
por: Sanz, Silvia, et al.
Publicado: (2019)

Fucosyltransferase 2: A Genetic Risk Factor for Intestinal Diseases
por: Hu, Mingyang, et al.
Publicado: (2022)

Ovalbumin-Induced Epithelial Activation Directs Monocyte-Derived Dendritic Cells to Instruct Type 2 Inflammation in T Cells Which Is Differentially Modulated by 2′-Fucosyllactose and 3-Fucosyllactose
por: Zuurveld, Marit, et al.
Publicado: (2022)

Influence of 2′-fucosyllactose and galacto-oligosaccharides on the growth and adhesion of Streptococcus mutans
por: Salli, K., et al.
Publicado: (2020)

Fucoidan But Not 2′-Fucosyllactose Inhibits Human Norovirus Replication in Zebrafish Larvae
por: Tan, Malcolm Turk Hsern, et al.
Publicado: (2021)

Effects of Bifidobacterium with the Ability of 2′-Fucosyllactose Utilization on Intestinal Microecology of Mice
por: Mao, Bingyong, et al.
Publicado: (2022)

2-Fucosyllactose Metabolism by Bifidobacteria Promotes Lactobacilli Growth in Co-Culture
por: Nogacka, Alicja M., et al.
Publicado: (2023)

Development of immunoassays for the detection of kanamycin in veterinary fields
por: Jin, Yong, et al.
Publicado: (2006)

Determination of Kanamycin by High Performance Liquid Chromatography
por: Zhang, Xingping, et al.
Publicado: (2019)

Smartphone-based kanamycin sensing with ratiometric FRET
por: Umrao, Saurabh, et al.
Publicado: (2019)

Oligofructose alone and in combination with 2′fucosyllactose induces physiologically relevant changes in γ-aminobutyric acid and organic acid production compared to sole 2′fucosyllactose supplementation: an in vitro study
por: Jackson, Peter Philip James, et al.
Publicado: (2023)

Effects of Androgen Receptor Inhibition on Kanamycin-Induced Hearing Loss in Rats
por: Chun, Kyung-Ju, et al.
Publicado: (2021)

Fucosyltransferase 1 and 2 play pivotal roles in breast cancer cells
por: Lai, Tai-Yu, et al.
Publicado: (2019)

Fucosyltransferase 2 inhibitors: Identification via docking and STD-NMR studies
por: Zafar, Humaira, et al.
Publicado: (2021)

Correlation between phenotypic and genotypic drug resistance to kanamycin and amikacin in clinical isolates of Mycobacterium tuberculosis
por: Ahmadi, Azam, et al.
Publicado: (2020)

Post-Synthetic Defucosylation of AGP by Aspergillus nidulans α-1,2-Fucosidase Expressed in Arabidopsis Apoplast Induces Compensatory Upregulation of α-1,2-Fucosyltransferases
por: Pogorelko, Gennady V., et al.
Publicado: (2016)

Pravastatin Administration Alleviates Kanamycin-Induced Cochlear Injury and Hearing Loss
por: Lee, Chang Ho, et al.
Publicado: (2022)

2′-Fucosyllactose Increases the Abundance of Blautia in the Presence of Extracellular Fucosidase-Possessing Bacteria
por: Horigome, Ayako, et al.
Publicado: (2022)

Effect of Rotavirus Infection and 2′-Fucosyllactose Administration on Rat Intestinal Gene Expression
por: Sáez-Fuertes, Laura, et al.
Publicado: (2023)

Structure and dynamics of the Arabidopsis O-fucosyltransferase SPINDLY
por: Kumar, Shivesh, et al.
Publicado: (2023)

Bifidobacterium infantis Metabolizes 2′Fucosyllactose-Derived and Free Fucose Through a Common Catabolic Pathway Resulting in 1,2-Propanediol Secretion
por: Dedon, Liv R., et al.
Publicado: (2020)

Functional characterization of Schistosoma mansoni fucosyltransferases in Nicotiana benthamiana plants
por: van Noort, Kim, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_ebrki745j09bl7j6sf95fd3rsh