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Hypoxia induces purinergic receptor signaling to disrupt endothelial barrier function

Blood-brain-barrier permeability is regulated by endothelial junctional proteins and is vital in limiting access to and from the blood to the CNS. When stressed, several cells, including endothelial cells, can release nucleotides like ATP and ADP that signal through purinergic receptors on these cel...

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Detalles Bibliográficos
Autores principales: Raghavan, Somasundaram, Brishti, Masuma Akter, Collier, Daniel Mohr, Leo, M. Dennis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9720161/
https://www.ncbi.nlm.nih.gov/pubmed/36479340
http://dx.doi.org/10.3389/fphys.2022.1049698