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Hypoxia induces purinergic receptor signaling to disrupt endothelial barrier function
Blood-brain-barrier permeability is regulated by endothelial junctional proteins and is vital in limiting access to and from the blood to the CNS. When stressed, several cells, including endothelial cells, can release nucleotides like ATP and ADP that signal through purinergic receptors on these cel...
Autores principales: | Raghavan, Somasundaram, Brishti, Masuma Akter, Collier, Daniel Mohr, Leo, M. Dennis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9720161/ https://www.ncbi.nlm.nih.gov/pubmed/36479340 http://dx.doi.org/10.3389/fphys.2022.1049698 |
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