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Hijacking the human complement inhibitor C4b-binding protein by the sporozoite stage of the Plasmodium falciparum parasite

The complement system is considered the first line of defense against pathogens. Hijacking complement regulators from blood is a common evasion tactic of pathogens to inhibit complement activation on their surfaces. Here, we report hijacking of the complement C4b-binding protein (C4bp), the regulato...

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Detalles Bibliográficos
Autores principales: Khattab, Ayman, Rezola, Mikel, Barroso, Marta, Kyrklund, Mikael, Pihlajamaa, Tero, Freitag, Tobias L., van Gemert, Geert-Jan, Bousema, Teun, Permi, Perttu, Turunen, Ossi, Sauerwein, Robert, Luty, Adrian J. F., Meri, Seppo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9720182/
https://www.ncbi.nlm.nih.gov/pubmed/36479121
http://dx.doi.org/10.3389/fimmu.2022.1051161