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Novel engineered chimeric engulfment receptors trigger T cell effector functions against SIV-infected CD4+ T cells

Adoptive therapy with genetically engineered T cells offers potential for infectious disease treatment in immunocompromised persons. HIV/simian immunodeficiency virus (SIV)-infected cells express phosphatidylserine (PS) early post infection. We tested whether chimeric engulfment receptor (CER) T cel...

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Detalles Bibliográficos
Autores principales: Corey, Daniel, Haeseleer, Francoise, Hou, Joe, Corey, Lawrence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9720250/
https://www.ncbi.nlm.nih.gov/pubmed/36514789
http://dx.doi.org/10.1016/j.omtm.2022.11.004