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Novel engineered chimeric engulfment receptors trigger T cell effector functions against SIV-infected CD4+ T cells
Adoptive therapy with genetically engineered T cells offers potential for infectious disease treatment in immunocompromised persons. HIV/simian immunodeficiency virus (SIV)-infected cells express phosphatidylserine (PS) early post infection. We tested whether chimeric engulfment receptor (CER) T cel...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9720250/ https://www.ncbi.nlm.nih.gov/pubmed/36514789 http://dx.doi.org/10.1016/j.omtm.2022.11.004 |