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Friends in need: How chaperonins recognize and remodel proteins that require folding assistance

Chaperonins are biological nanomachines that help newly translated proteins to fold by rescuing them from kinetically trapped misfolded states. Protein folding assistance by the chaperonin machinery is obligatory in vivo for a subset of proteins in the bacterial proteome. Chaperonins are large oligo...

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Detalles Bibliográficos
Autores principales: Stan, George, Lorimer, George H., Thirumalai, D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9720267/
https://www.ncbi.nlm.nih.gov/pubmed/36479385
http://dx.doi.org/10.3389/fmolb.2022.1071168