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Human gut microbiota-reactive DP8α regulatory T cells, signature and related emerging functions

In mice, microbiota-induced Tregs both maintain intestinal homeostasis and provide resistance to immuno-pathologies in the adult. Identifying their human functional counterpart therefore represents an important goal. We discovered, in the human colonic lamina propria and blood, a FoxP3-negative IL-1...

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Detalles Bibliográficos
Autores principales: Jotereau, Francine, Alameddine, Joudy, Teusan, Raluca, Pédron, Annabelle, Jouand, Nicolas, Altare, Frédéric, Godefroy, Emmanuelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9720269/
https://www.ncbi.nlm.nih.gov/pubmed/36479125
http://dx.doi.org/10.3389/fimmu.2022.1026994