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Targeting Cellular Metabolism With CPI-613 Sensitizes Pancreatic Cancer Cells to Radiation Therapy

PURPOSE: Local tumor progression is a cause of significant morbidity and mortality in patients with pancreatic ductal adenocarcinoma (PDAC) with surgically unresectable disease. Novel and effective approaches to accomplish durable local control are urgently needed. We tested whether CPI-613 (devimis...

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Detalles Bibliográficos
Autores principales: Khan, Husain Yar, Kamgar, Mandana, Aboukameel, Amro, Bannoura, Sahar, Chung, Brian Y., Li, Yiwei, Hallak, Mohammed Najeeb Al, Philip, Philip A., Tsai, Susan, Luther, Sanjeev, Hall, William A., Azmi, Asfar S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9720358/
https://www.ncbi.nlm.nih.gov/pubmed/36479231
http://dx.doi.org/10.1016/j.adro.2022.101122