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Comparative sensitivity of automated (Abbott M2000) and manual plasma HIV-1 RNA PCR assays for the detection of persistent viremia after long-term antiretroviral therapy

BACKGROUND: The ability of automated, FDA-cleared plasma HIV-1 RNA assays to detect low-level viremia, compared to manual, highly sensitive research-only methods, is not well-defined. We therefore tested paired plasma samples from people with HIV-1 (PWH) on long-term antiretroviral therapy (ART) wit...

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Detalles Bibliográficos
Autores principales: Tosiano, Melissa A., Mar, Hanna, Hoeth, Dianna, Eron, Joseph J., Gandhi, Rajesh T., McMahon, Deborah K., Bosch, Ronald J., Mellors, John W., Cyktor, Joshua C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9720429/
https://www.ncbi.nlm.nih.gov/pubmed/36479541
http://dx.doi.org/10.1016/j.jve.2022.100095