Molecular Dynamics Simulations of the Cardiac Ryanodine Receptor Type 2 (RyR2) Gating Mechanism

[Image: see text] Mutations in the cardiac ryanodine receptor type 2 (RyR2) have been linked to fatal cardiac arrhythmias such as catecholaminergic polymorphic ventricular tachycardia (CPVT). While many CPVT mutations are associated with an increase in Ca(2+) leak from the sarcoplasmic reticulum, th...

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Detalles Bibliográficos
Autores principales: Greene, D’Artagnan, Barton, Michael, Luchko, Tyler, Shiferaw, Yohannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9720719/
https://www.ncbi.nlm.nih.gov/pubmed/36384028
http://dx.doi.org/10.1021/acs.jpcb.2c03031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9720719/
https://www.ncbi.nlm.nih.gov/pubmed/36384028
http://dx.doi.org/10.1021/acs.jpcb.2c03031

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