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Complexity of progranulin mechanisms of action in mesothelioma

BACKGROUND: Mesothelioma is an aggressive disease with limited therapeutic options. The growth factor progranulin plays a critical role in several cancer models, where it regulates tumor initiation and progression. Recent data from our laboratories have demonstrated that progranulin and its receptor...

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Detalles Bibliográficos
Autores principales: Ventura, Elisa, Xie, Christopher, Buraschi, Simone, Belfiore, Antonino, Iozzo, Renato V., Giordano, Antonio, Morrione, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9720952/
https://www.ncbi.nlm.nih.gov/pubmed/36471440
http://dx.doi.org/10.1186/s13046-022-02546-4