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Complexity of progranulin mechanisms of action in mesothelioma
BACKGROUND: Mesothelioma is an aggressive disease with limited therapeutic options. The growth factor progranulin plays a critical role in several cancer models, where it regulates tumor initiation and progression. Recent data from our laboratories have demonstrated that progranulin and its receptor...
Autores principales: | Ventura, Elisa, Xie, Christopher, Buraschi, Simone, Belfiore, Antonino, Iozzo, Renato V., Giordano, Antonio, Morrione, Andrea |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9720952/ https://www.ncbi.nlm.nih.gov/pubmed/36471440 http://dx.doi.org/10.1186/s13046-022-02546-4 |
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