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Time-resolved microfluidics unravels individual cellular fates during double-strand break repair

BACKGROUND: Double-strand break repair (DSBR) is a highly regulated process involving dozens of proteins acting in a defined order to repair a DNA lesion that is fatal for any living cell. Model organisms such as Saccharomyces cerevisiae have been used to study the mechanisms underlying DSBR, includ...

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Detalles Bibliográficos
Autores principales: Vertti-Quintero, Nadia, Levien, Ethan, Poggi, Lucie, Amir, Ariel, Richard, Guy-Franck, Baroud, Charles N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9720956/
https://www.ncbi.nlm.nih.gov/pubmed/36464673
http://dx.doi.org/10.1186/s12915-022-01456-3