Cargando…
Time-resolved microfluidics unravels individual cellular fates during double-strand break repair
BACKGROUND: Double-strand break repair (DSBR) is a highly regulated process involving dozens of proteins acting in a defined order to repair a DNA lesion that is fatal for any living cell. Model organisms such as Saccharomyces cerevisiae have been used to study the mechanisms underlying DSBR, includ...
Autores principales: | Vertti-Quintero, Nadia, Levien, Ethan, Poggi, Lucie, Amir, Ariel, Richard, Guy-Franck, Baroud, Charles N. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9720956/ https://www.ncbi.nlm.nih.gov/pubmed/36464673 http://dx.doi.org/10.1186/s12915-022-01456-3 |
Ejemplares similares
-
Combinatorial drug screening on 3D Ewing sarcoma spheroids using droplet-based microfluidics
por: Fevre, Romain, et al.
Publicado: (2023) -
The Fate of Oxidative Strand Breaks in Mitochondrial DNA
por: Trombly, Genevieve, et al.
Publicado: (2023) -
Resection and repair of a Cas9 double-strand break at CTG trinucleotide repeats induces local and extensive chromosomal deletions
por: Mosbach, Valentine, et al.
Publicado: (2020) -
DNA ligase III acts as a DNA strand break sensor in the cellular orchestration of DNA strand break repair
por: Abdou, Ismail, et al.
Publicado: (2015) -
ATM specifically mediates repair of double-strand breaks with blocked DNA ends
por: Álvarez-Quilón, Alejandro, et al.
Publicado: (2014)