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Serum immunoglobulin G and mucosal immunoglobulin A antibodies from prepandemic samples collected in Kilifi, Kenya, neutralize SARS-CoV-2 in vitro

OBJECTIVES: Many regions of Africa have experienced lower COVID-19 morbidity and mortality than Europe. Pre-existing humoral responses to endemic human coronaviruses (HCoV) may cross-protect against SARS-CoV-2. We investigated the neutralizing capacity of SARS-CoV-2 spike reactive and nonreactive im...

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Detalles Bibliográficos
Autores principales: Nyagwange, James, Kutima, Bernadette, Mwai, Kennedy, Karanja, Henry K., Gitonga, John N., Mugo, Daisy, Sein, Yiakon, Wright, Daniel, Omuoyo, Donwilliams O., Nyiro, Joyce U., Tuju, James, Nokes, D. James, Agweyu, Ambrose, Bejon, Philip, Ochola-Oyier, Lynette I., Scott, J. Anthony G., Lambe, Teresa, Nduati, Eunice, Agoti, Charles, Warimwe, George M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9721188/
https://www.ncbi.nlm.nih.gov/pubmed/36476349
http://dx.doi.org/10.1016/j.ijid.2022.11.041