A rapid in vitro assay for evaluating the effects of acetylcholinesterase inhibitors and reactivators in the rat basolateral amygdala

We established a novel brain slice assay to test the ability of acetylcholinesterase (AChE) reactivators to prevent ACh-induced M1 muscarinic acetylcholine receptor (mAChR) dependent hyperexcitability observed after exposure to the organophosphate (OP)-based AChE inhibitor and sarin surrogate 4-nitr...

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Detalles Bibliográficos
Autores principales: Thinschmidt, Jeffrey S., Harden, Scott W., King, Michael A., Talton, James D., Frazier, Charles J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cellular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9721344/
https://www.ncbi.nlm.nih.gov/pubmed/36479275
http://dx.doi.org/10.3389/fncel.2022.1066312

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9721344/
https://www.ncbi.nlm.nih.gov/pubmed/36479275
http://dx.doi.org/10.3389/fncel.2022.1066312

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