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High-content CRISPR screening in tumor immunology

CRISPR screening is a powerful tool that links specific genetic alterations to corresponding phenotypes, thus allowing for high-throughput identification of novel gene functions. Pooled CRISPR screens have enabled discovery of innate and adaptive immune response regulators in the setting of viral in...

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Detalles Bibliográficos
Autores principales: Holcomb, Erin A., Pearson, Ashley N., Jungles, Kassidy M., Tate, Akshay, James, Jadyn, Jiang, Long, Huber, Amanda K., Green, Michael D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9721350/
https://www.ncbi.nlm.nih.gov/pubmed/36479127
http://dx.doi.org/10.3389/fimmu.2022.1041451