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Spike protein receptor-binding domains from SARS-CoV-2 variants of interest bind human ACE2 more tightly than the prototype spike protein

Several SARS-CoV-2 variants of interest (VOI) have emerged since this virus was first identified as the etiologic agent responsible for COVID-19. Some of these variants have demonstrated differences in both virulence and transmissibility, as well as in evasion of immune responses in hosts vaccinated...

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Detalles Bibliográficos
Autores principales: Charles, Jermilia, McCann, Nathan, Ploplis, Victoria A., Castellino, Francis J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9721372/
https://www.ncbi.nlm.nih.gov/pubmed/36525925
http://dx.doi.org/10.1016/j.bbrc.2022.12.011