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Spike protein receptor-binding domains from SARS-CoV-2 variants of interest bind human ACE2 more tightly than the prototype spike protein
Several SARS-CoV-2 variants of interest (VOI) have emerged since this virus was first identified as the etiologic agent responsible for COVID-19. Some of these variants have demonstrated differences in both virulence and transmissibility, as well as in evasion of immune responses in hosts vaccinated...
Autores principales: | Charles, Jermilia, McCann, Nathan, Ploplis, Victoria A., Castellino, Francis J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9721372/ https://www.ncbi.nlm.nih.gov/pubmed/36525925 http://dx.doi.org/10.1016/j.bbrc.2022.12.011 |
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