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Novel H7N9 influenza immunogen design enhances mobilization of seasonal influenza T cell memory in H3N2 pre-immune mice

Strategies that improve influenza vaccine immunogenicity are critical for the development of vaccines for pandemic preparedness. Hemagglutinin (HA)-specific CD4(+) T cell epitopes support protective B cell responses against seasonal influenza. However, in the case of avian H7N9, which poses a pandem...

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Detalles Bibliográficos
Autores principales: Moise, Leonard, Meyers, Lauren M., Jang, Hyesun, Grizotte-Lake, Mayara, Boyle, Christine M., McGonnigal, Bethany, Ge, Pan, Ross, Ted M., De Groot, Anne S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9721412/
https://www.ncbi.nlm.nih.gov/pubmed/35704783
http://dx.doi.org/10.1080/21645515.2022.2082191