Piezo1-mediated fluid shear stress promotes OPG and inhibits RANKL via NOTCH3 in MLO-Y4 osteocytes

Piezo1, a mechanosensitive ion channel, participates in a variety of biological processes in maintaining bone homeostasis. As the most abundant cells in bones of the mammals, osteocytes play an essential role in bone formation, remodeling, and bone mass maintenance. Here, by exposing MLO-Y4 osteocyt...

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Detalles Bibliográficos
Autores principales: Liu, Zhongcheng, Tang, Yuchen, He, Liangzhi, Geng, Bin, Lu, Fan, He, Jinwen, Yi, Qiong, Liu, Xuening, Zhang, Kun, Wang, Lifu, Xia, Yayi, Jiang, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9721416/
https://www.ncbi.nlm.nih.gov/pubmed/35754337
http://dx.doi.org/10.1080/19336950.2022.2085379

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9721416/
https://www.ncbi.nlm.nih.gov/pubmed/35754337
http://dx.doi.org/10.1080/19336950.2022.2085379

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