Novel benzo chromene derivatives: design, synthesis, molecular docking, cell cycle arrest, and apoptosis induction in human acute myeloid leukemia HL-60 cells

A series of benzo[h]chromenes, benzo[f]chromenes, and benzo[h]chromeno[2,3-d]pyrimidines were prepared. All the newly synthesised compounds were selected by National Cancer Institute for single-dose testing against 60 cell lines. Benzo[h]chromenes 5a and 6a showed promising anti-cancer activity and...

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Detalles Bibliográficos
Autores principales: Abd El-Hameed, Rania H., Mohamed, Mosaad S., Awad, Samir M., Hassan, Bardes B., Khodair, Marwa Abd El-Fattah, Mansour, Yara E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9721423/
https://www.ncbi.nlm.nih.gov/pubmed/36458403
http://dx.doi.org/10.1080/14756366.2022.2151592

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9721423/
https://www.ncbi.nlm.nih.gov/pubmed/36458403
http://dx.doi.org/10.1080/14756366.2022.2151592

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